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Respiratory

G144 THE USE OF CONTINUOUS GLUCOSE MONITORING TO DETECT CYSTIC FIBROSIS RELATED DIABETES IN ADOLESCENTS WITH CYSTIC FIBROSIS
R. Pryce¹, M. Pierrepoint², I. Doull¹, I. Bowler³, J. Barton³, J. Hambleton³, S. Hall¹, K. Azzopardi¹, C. Bretland¹, L. Lowes¹, J. W. Gregory¹.¹University Hospital of Wales, Cardiff, UK; ²Nevill Hall Hospital, Abergavenny, UK; ³Royal Gwent Hospital, Newport, UK

Background and Aim: Improved survival in adolescents with cystic fibrosis has led to complications including cystic fibrosis related diabetes. Cystic fibrosis related diabetes is associated with declining respiratory status and weight, higher morbidity, and mortality. These changes may precede abnormalities in glycaemic control detected by the oral glucose tolerance test (OGTT) by up to 4 years. The optimum screening test for cystic fibrosis related diabetes remains controversial and many argue the OGTT is the gold standard. However, there is evidence the OGTT may not detect transient hyperglycaemia and treating these patients improves clinical parameters. We therefore assessed whether continuous glucose . . . [Full text of this article]