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Bone

G136 A LONGITUDINAL STUDY OF LOWER LIMB LENGTH AND TIBIAL SPEED OF SOUND IN PRETERM INFANTS: RELATIONSHIP WITH BIOCHEMICAL MARKERS OF BONE TURNOVER
J. May¹, J. Dutton², J. Morris³, W. D. Fraser², A. J. B. Emmerson¹, M. Z. Mughal⁴.¹Neonatal Medicine, St Mary’s Hospital for Women & Children, Manchester, UK; ²Clinical Biochemistry, Royal Liverpool Hospital, Liverpool, UK; ³Medical Statistics, University of Manchester, Manchester, UK; ⁴Paediatric Medicine, St Mary’s Hospital for Women & Children, Manchester, UK

Background: In healthy singleton infants 31 to 42 weeks gestation, tibial speed of sound (m/s) measured at median age of 2.1 days after birth increased with gestational age.

Method: In this longitudinal study we measured the knee–heel limb length (mm) using an electronic neonatal knemometer (FORCE Institutes, Denmark) and tibial speed of sound using the Sunlight Omnisense quantitative ultrasound device (Sunlight Medical Ltd., Israel), in the same limb, in 82 preterm infants. The median (range) gestation and birth weight of infants was 27 weeks (23 to 37.6 weeks) and 903 grams (418 . . . [Full text of this article]