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Oncology and haematology

G129 EARLY COGNITIVE OUTCOME IN CHILDREN TREATED FOR BRAIN TUMOURS IN COMPARISON WITH MATCHED NORMAL CONTROLS
R. Shortman¹, R. J. McCarter¹, A. Penn², S. Lowis², M. Stevens², A. Curran¹, P. M. Sharples².¹Frenchay Hospital, Bristol, UK; ²Bristol Royal Hospital for Children, Bristol, UK

Introduction: Brain tumours are the second most common childhood malignancy. There is evidence that cognitive function is reduced in long term brain tumour survivors but few data exist concerning early outcome. The relative contributions of tumour, surgery, and radiotherapy/chemotherapy to cognitive outcome remain to be defined.

Aims: To measure cognitive outcome in children with brain tumours one month after diagnosis.

Design Methods: Longitudinal prospective study of children with brain tumours admitted to the Regional Neuroscience Centre compared with normal children matched for age, sex, and socioeconomic status. Intellectual outcome was assessed using the Wechsler Intelligence Scale for Children (WISC III UK), the Wechsler Primary and Preschool Scale of Intelligence – Revised. Attention was assessed using the . . . [Full text of this article]