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Perinatal

G8 CORRELATION OF CONTINUOUS VIDEO EEG MONITORING AND SERIAL LACTATE MEASUREMENTS IN HYPOXIC ISCHAEMIC ENCEPHALOPATHY
D. M. Murray¹, G. B. Boylan¹, S. Connolly², B. P. Murphy¹, C. A. Ryan¹.¹United Maternity Services, Cork, Ireland; ²St Vincent’s University Hospital, Dublin, Ireland

Background: EEG monitoring is useful in the early diagnosis and prognosis of hypoxic ischaemic encephalopathy (HIE) but is not always available in the neonatal intensive care unit. Arterial lactate measurements at 30 min of age have shown promise in predicting which infants are at increased risk of HIE, and proton magnetic resonance spectroscopy has shown persistently raised cerebral lactate up to 1 month post-delivery in infants with HIE.

Aim: To establish the relationship between initial and serial lactate measurements and the severity of EEG changes in full term babies with hypoxic ischaemic encephalopathy.

Method: A prospective study from a large maternity service (6000 deliveries per annum). Continuous video EEG monitoring for 24–72 hours was performed within 6 hours of birth. . . . [Full text of this article]