© 2005 BMJ Publishing Group & Royal College of Paediatrics and Child Health
PERSPECTIVE
Respiratory medicine
Respiratory support of infants with bronchiolitis related apnoea: is there a role for negative pressure?
Correspondence to:
Correspondence to:
Dr J Henderson
University of Bristol, Royal Hospital for Children, Paul O’Gorman Building, Department of Respiratory Medicine, Upper Maudlin Street, Bristol BS2 8BJ, UK; a.j.henderson@bris.ac.uk
Commentary on the paper by Al-balkhi et al (see page 288)
Abbreviations: CNEP, continuous negative extrathoracic pressure; COPD, chronic obstructive pulmonary disease; CPAP, continuous positive airway pressure; NPV, negative pressure ventilation; RSV, respiratory syncytial virus
Keywords: bronchiolitis; intensive care; respiratory syncytial virus; ventilators
| The first 150 words of the full text of this article appear below. |
Negative pressure ventilation is not new. Indeed the first practical ventilator for human subjects was the iron lung designed in the late 1920s to provide ventilatory assistance to patients with poliomyelitis.1 However, negative pressure ventilation has been largely superseded by developments of positive pressure ventilation equipment and techniques, including non-invasive positive pressure ventilation. In this issue of the journal, Al-balkhi and colleagues suggest a role for negative pressure ventilation in the treatment of infants with apnoea associated with bronchiolitis.2 So is negative pressure ventilation on the brink of a comeback or should it be properly consigned to history?
Negative pressure ventilation (NPV) relies on the application of a subatmospheric pressure to the thorax, which is transmitted to a reduction of intrapleural pressure, leading to expansion of the lungs. By cycling the pressure and allowing passive deflation of the lungs as the negative intrapleural pressure rises, alveolar ventilation can
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- Review of treatment of bronchiolitis related apnoea in two centres
- A Al-balkhi, H Klonin, K Marinaki, D P Southall, D A Thomas, P Jones, and M P Samuels
Arch. Dis. Child. 2005 90: 288-291.[Abstract] [Full Text] [PDF]
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