© 2004 BMJ Publishing Group & Royal College of Paediatrics and Child Health
Atoms
| The first 150 words of the full text of this article appear below. |
Treating children with asthma has become increasingly difficult, although admittedly I do not have fond memories of measuring and adjusting theophylline levels in the 1970s and 1980s. Currently, virtually all guidelines for the treatment of children with persistent asthma mandate the use of inhaled corticosteroids (ICS). While in the past there were only a limited number of ICS, now there are many preparations available, all coming in different strengths. Masoli and colleagues from New Zealand present the results of a systematic review of the efficacy of inhaled fluticasone proprionate, suggesting a dose-response relationship that plateaus between 100 and 200 µg per day. In an accompanying perspective, George Russell comments on two critical aspects of asthma management—adherence and titration to the lowest effective dose of ICS. Many questions remain. For example, at what dose of ICS should leukotriene receptor antagonists or long acting ß2 agonists be added to "spare" the steroid
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
Relevant Articles
- The use of inhaled corticosteroids during childhood: plus ça change...
- G Russell
Arch. Dis. Child. 2004 89: 893-895.[Extract] [Full Text] [PDF]
- Systematic review of the dose-response relation of inhaled fluticasone propionate
- M Masoli, M Weatherall, S Holt, and R Beasley
Arch. Dis. Child. 2004 89: 902-907.[Abstract] [Full Text] [PDF]
- Infant colic and feeding difficulties
- C Miller-Loncar, R Bigsby, P High, M Wallach, and B Lester
Arch. Dis. Child. 2004 89: 908-912.[Abstract] [Full Text] [PDF]
- Diagnosing and treating attentional difficulties: a nationwide survey
- I McKenzie and C Wurr
Arch. Dis. Child. 2004 89: 913-916.[Abstract] [Full Text] [PDF]
- Capillary refill: prognostic value in Kenyan children
- A Pamba and K Maitland
Arch. Dis. Child. 2004 89: 950-955.[Abstract] [Full Text] [PDF]
- Are bedside features of shock reproducible between different observers?
- H Otieno, E Were, I Ahmed, E Charo, A Brent, and K Maitland
Arch. Dis. Child. 2004 89: 977-979.[Abstract] [Full Text] [PDF]
This article has been cited by other articles:
-
(2005). Respiratory. Arch. Dis. Child.
90: A59-A63
[Full Text]
- Full Text
- Full Text (PDF)
- Submit a response
- Alert me when this article is cited
- Alert me when eLetters are posted
- Alert me if a correction is posted
Services
- Email this link to a friend
- Similar articles in ADC Online
- Add article to my folders
- Download to citation manager
- Request Permissions
Citing Articles
Google Scholar
PubMed
Topic Collections
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
