© 2003 BMJ Publishing Group & Royal College of Paediatrics and Child Health
Abstracts
Endocrinology and diabetes
| The first 150 words of the full text of this article appear below. |
M. Chalumeau, C.G. Hadjiathanasiou, S.M. Ng, A. Cassio, D. Mul, M. Cisternino, C.J. Partsch, C. Theodoridis, M. Didi, E. Cacciari, W. Oostdijk, A. Borghesi, W.G. Sippell, G. Bréart, R. Brauner.
INSERM U149, Paris-France and Pediatric Endocrinology Departments in Athens-Greece, Liverpool-UK, Bologna and Pavia-Italy, Rotterdam and Leiden-The Netherlands, Kiel-Germany, Paris-France
Background: Central precocious puberty (CPP) reveals an occult intracranial lesion (OICL) in 5–10% of affected girls. Systematic brain imaging is recommended but is normal and then not contributive in 90–95% of the cases. Recently, two American groups formulated distinct guidelines to select girls with CPP who require brain imaging. A previous single-center study found those recommendations to lack sensitivity to identify OICL and had proposed a 100% sensitivity, evidence-based, diagnosis rule, combining two independent predictors of OICL: age at puberty onset (ie, breast development) <6 years, and estradiol (E2) level >45th percentile of girls with idiopathic CPP.
Aim: To validate our
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
- Full Text
- Full Text (PDF)
- Submit a response
- Alert me when this article is cited
- Alert me when eLetters are posted
- Alert me if a correction is posted
Services
- Email this link to a friend
- Similar articles in ADC Online
- Add article to my folders
- Download to citation manager
- Request Permissions
Citing Articles
Google Scholar
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
