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BACCH and child development and disability

G149. NATIONAL STUDY OF FIVE YEAR OLD ICSI CONCEIVED CHILDREN COMPARED WITH NATURALLY AND IVF CONCEIVED CONTROLS
A.G. Sutcliffe, C.J. Peters, X. Chrysostomou, P. Edwards.

Department of Child Health, Royal Free Hospital Medical School, UCL

Aims: To investigate the physical and neurodevelopmental wellbeing of ICSI, conventional IVF and naturally conceived controls five year olds.

Methods: IVF and ICSI children were recruited through fertility clinics, naturally conceived children were recruited through schools/nurseries. Children were singleton, first born and caucasian. A paediatrician ascertained a sociodemographic, medical and developmental history and performed a physical examination including visual testing, pure tone audiometry, measurement of growth and ascertainment of congenital abnormalities. A psychologist (who was blinded to conception type) assessed the child using WPPSI-R, McCarthy, and Bene-Anthony family relations test.

Results: 188 ICSI, 159 IVF and 163 controls were assessed. A range of sociodemograhic factors, including social class, parental level of education, maternal smoking, and parental drinking were comparable between groups. Mean maternal age of study children, 34.4 years, was comparable to . . . [Full text of this article]

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