© 2003 BMJ Publishing Group & Royal College of Paediatrics and Child Health
Abstracts
Computers
| The first 150 words of the full text of this article appear below. |
A.D. Cowley, S.V. Beath, C. Cummins2, D. Porter, I. van Mourik, P.J. McKiernan, D.A. Kelly.
The Liver Unit and 2Statistics Dept, Birmingham Childen’s Hospital, Steelhouse Lane, Birmingham, B4 6NH
Aims: To develop an audit tool, which measures disease severity and clinical dependency in children with liver disease.
Methods: The initial score was based on known prognostic variables (J Malatack, et al) used in acute and chronic liver disease. Between 1997 and 2001 the score was modified four times and reduced to comprise 10 key variables as follows: Aspartate transaminase, prothrombin time, albumin, bilirubin, ascites, nutrition, organ dysfunction, blood product support, sepsis and IV access. The first five parameters are specific to liver disease and the last five are generic dependency parameters. The score was validated by examining 1) face validity, 2) construct validity, 3) internal consistency (Cronbach’s Alpha). Inter-observer differences were evaluated by the methods of Bland and
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