© 2003 BMJ Publishing Group & Royal College of Paediatrics and Child Health
LEADING ARTICLE
Transplantation
Renal transplantation
1 Department of Paediatric Nephrology, Royal Manchester Children’s Hospital, Pendlebury, Manchester M27 4HA, UK
2 UK Transplant, Fox Den Road, Stoke Gifford, Bristol BS34 8RR, UK
Correspondence to:
Correspondence to:
Dr N J A Webb, Department of Paediatric Nephrology, Royal Manchester Children’s Hospital, Pendlebury, Manchester M27 4HA, UK;
n.webb@doctors.org.uk
Present outcomes and future challenges
Keywords: renal transplantation; organ donation; graft; immunosuppressive
| The first 150 words of the full text of this article appear below. |
Renal transplantation is undoubtedly the treatment of choice for children with end stage renal failure. While great advances have been made in the field of renal replacement therapy, the provision of dialysis and associated therapies places major restrictions on the child and their family. Poor weight gain and linear growth may necessitate supplementary feeding and/or recombinant growth hormone, and further dietary restrictions are imposed by the potassium and phosphate restricted diets that are necessary. Children also require oral and subcutaneous drug therapy for the treatment and prevention of anaemia, renal osteodystrophy, and hypertension. Psychomotor development is retarded and this is compounded by the imposition on normal childhood activities and interference with schooling associated with haemodialysis and, to a lesser extent, peritoneal dialysis.
The restoration of normal or near normal renal function by transplantation allows a number of these difficult and time consuming therapies to stop and may facilitate better
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Arch. Dis. Child. 2003 88: 839.[Extract] [Full Text] [PDF]
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