© 2002 Archives of Disease in Childhood
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Discontinuing anticonvulsant medication in children
Report by Edited by Bob Phillips
Consultant Paediatricians, York District Hospital, UK
| The first 150 words of the full text of this article appear below. |
A12 year old girl with primary generalised epilepsy comes to clinic for review. She has been seizure free for two years on sodium valproate 600 mg twice daily. Following discussion with her and her mother, an agreement is reached to withdraw the medication. You advise that the medication should be tapered off over a six week period. At this point the mother informs you that when she had her own anticonvulsant medication withdrawn, this was reduced over a six month period. She questioned whether it was appropriate to reduce the medication so quickly and requested evidence to support the recommendation, raising concerns about the possibility of a higher risk of seizure recurrence.
In a child with primary generalised epilepsy [patient] does the rate of withdrawal of anticonvulsants [intervention] affect rate of seizure recurrence or other adverse event [outcome]?
The Cochrane library1 search terms "epilepsy" or "anticonvulsants" yielded no
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