LEADING ARTICLE

Infection

Advances in the prevention and treatment of paediatric HIV infection in the United Kingdom

M Sharland¹, D M Gibb², G Tudor-Williams³

¹ Paediatric Infectious Diseases Unit, St George’s Hospital, Blackshaw Road, London SW17 0QT, UK
² Clinical Trials Unit, Medical Research Council, 222 Euston Road, London NW1 2DA, UK
³ Paediatric Infectious Diseases Unit, St Mary’s Hospital, 6th Floor, QEQM Wing, Praed St, London W2 1NY, UK

Correspondence to:
Correspondence to:
Dr M Sharland, Paediatric Infectious Diseases Unit, St George’s Hospital, Blackshaw Road, London SW17 0QT, UK;
msharlan@sghms.ac.uk

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A summary of recent developments

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Keywords: HIV; AIDS

Abbreviations: ART, antiretroviral therapy; DoH, Department of Health; HAART, highly active antiretroviral therapy; ICH, Institute of Child Health; MTCT, mother to child transmission; PCP, Pneumocystis carinii pneumonia

The first 150 words of the full text of this article appear below.

In the five years since our last review there have been considerable advances, both in the prevention of mother to child transmission (MTCT) of HIV, and in the treatment of HIV infected children with highly active antiretroviral therapy (HAART).¹ There are now over 600 children living with HIV in the UK, the majority of whom were born to mothers who acquired HIV in Africa.² Currently, about two thirds live in London, but this may change if refugees continue to be dispersed to other parts of the country. Antenatal testing for HIV has been shown to be cost effective throughout the UK.³ However, although uptake of testing has increased in London, rates of detection of previously undiagnosed women during pregnancy are about 60% outside London.² HIV infected babies are still presenting seriously ill and dying with Pneumocystis carinii pneumonia (PCP) in the first months of life.⁴ In 1999 the Department . . . [Full text of this article]

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