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Archives of Disease in Childhood 2002;86:453; doi:10.1136/adc.86.6.453-a
Copyright © 2002 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health.
Archives of Disease in Childhood 2002;86:453
© 2002 Archives of Disease in Childhood

LETTER

Bordetella pertussis infection causing pulmonary hypertension

P Casano, M Pons Odena, F J Cambra, J M Martín, A Palomeque

Hospital Sant Joan de Déu, Unidad de Cuidados Intensivos Pediátricos, Passeig de Sant Joan de Déu, 2 080950, Esplugues de Llobregat, Barcelona, Spain; mpons@hsjdbcn.org

Keywords: Bordetella pertussis; pulmonary hypertension

In Spain the incidence of whooping cough is less than five cases per 100 000 inhabitants.1 Mortality rate is 0.4% in the United States, heart failure being one of the most frequent causes.2 Although cases of death due to Bordetella pertussis infection as a consequence of lung hypertension have been described previously,3–5 this complication is not very well known. Here we report a recent case and review the literature.

A 23 day old girl, who had had a pertussive cough for several days, was admitted with breathing difficulty of 12 hours duration. On admission she had tachycardia (heart rate 180 beats/min), tachypnoea (70 breaths/min), pyrexia (38°C), and haemoglobin saturation 90% without oxygen. A chest x ray revealed right superior and half lobe infiltrates. Blood analysis showed 53 x 109 leucocytes with left deviation and 33 mg/dl C reactive protein. Testing for respiratory syncitial virus was negative; direct immunofluorescence and culture . . . [Full text of this article]


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This article has been cited by other articles:

  • Singh, M., Lingappan, K. (2006). Whooping cough: the current scene.. Chest 130: 1547-1553 [Abstract] [Full Text]  
  • Hewlett, E. L., Edwards, K. M. (2005). Pertussis -- Not Just for Kids. NEJM 352: 1215-1222 [Full Text]  

eLetters:

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Pulmonary HT in bronchiolitis
Santhosh R Gopal
ADC Online, 24 May 2002 [Full text]
Mechanisms of pulmonary hypertension in bordetella pertussis
Mark J Peters, et al.
ADC Online, 10 Jun 2002 [Full text]
Re: Mechanisms of pulmonary hypertension in bordetella pertussis
Marti Pons, et al.
ADC Online, 12 Jun 2002 [Full text]
Role of Bordetella heat-labile toxin in pulmonary hypertension in pertussis
Mineo Watanabe, et al.
ADC Online, 9 Apr 2003 [Full text]

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