© 2002 Archives of Disease in Childhood
LETTER
Bordetella pertussis infection causing pulmonary hypertension
Hospital Sant Joan de Déu, Unidad de Cuidados Intensivos Pediátricos, Passeig de Sant Joan de Déu, 2 080950, Esplugues de Llobregat, Barcelona, Spain; mpons@hsjdbcn.org
Keywords: Bordetella pertussis; pulmonary hypertension
In Spain the incidence of whooping cough is less than five cases per 100 000 inhabitants.1 Mortality rate is 0.4% in the United States, heart failure being one of the most frequent causes.2 Although cases of death due to Bordetella pertussis infection as a consequence of lung hypertension have been described previously,35 this complication is not very well known. Here we report a recent case and review the literature.
A 23 day old girl, who had had a pertussive cough for several days, was admitted with breathing difficulty of 12 hours duration. On admission she had tachycardia (heart rate 180 beats/min), tachypnoea (70 breaths/min), pyrexia (38°C), and haemoglobin saturation 90% without oxygen. A chest x ray revealed right superior and half lobe infiltrates. Blood analysis showed 53 x 109 leucocytes with left deviation and 33 mg/dl C reactive protein. Testing for respiratory syncitial virus was negative; direct immunofluorescence and culture
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