© 2002 Archives of Disease in Childhood
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In the US there are over 800 over-the-counter medications for treating the common cold, and there are probably a similar number in European countries. Most parents set great store but paediatricians are sceptical.
Prejudice is all very well, but evidence is all the rage nowadays so we are pleased to publish Schroeder and Fahey's systematic review of RCTs of over the counter medicines for acute cough. It is instructive to look at their figure 1, detailing what must have been a pretty depressing journey through the literature: they immediately triaged 235 of 328 identified trials as inadequate and excluded a further 87 after review. Just six RCTs remained, all less than totally methodologically sound. For what they were worth, their results do not show any benefit of cough medicines over placebo.
Once again, the pointlessness of so many peer reviewed published papers is shown up, not that this will reduce
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