Letters to the editor
Recommendations for the management of galactosaemia
| The first 150 words of the full text of this article appear below. |
EDITOR,
Drs Garden and Davidson raise some very
important points concerning the best oestrogen preparation for long
term replacement in ovarian failure.1 Their comments are
principally directed at oestrogen replacement during adulthood rather
than pubertal induction. The latter is most easily effected using
ethinyl oestradiol, because suitable low dose preparations are
available so that puberty can be induced gradually over several years.
The issue of which oestrogen preparation should be used for long term
replacement in patients with hypogonadism is relevant not only to girls
with galactosaemia but also to those with Turner's syndrome and
hypopituitarism. The recommendation to use a combined oral
contraceptive preparation in a young woman who has completed pubertal
induction is based on practicality and convenience to the user.
The problem when choosing an oestrogen preparation once full pubertal
development has been achieved is that there is a paucity of evidence to
inform decision
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