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Asthma treatment and growth
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Introduction |
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It is generally acknowledged that asthma may have an effect on children's growth independent of any treatment they may be receiving. The many studies showing this have been reviewed recently by Russell in this journal.1 In summary, children with moderate to severe asthma may have a characteristic pattern of slowing of prepubertal growth, delayed puberty, and a late pubertal growth spurt, with catch up to an adult height within the expected target range. It is because of this effect that difficulties can arise in trying to separate the effects of asthma from the effects of any treatment in studies of growth in children with asthma.
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Oral corticosteroids |
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There is little doubt that oral corticosteroids such as
prednisolone can have a detrimental effect on growth. Martin et
al,2 in a prospective survey over 14 years, showed
that children who had received oral steroids were significantly shorter
than either asthmatic children who had not
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