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Arch Dis Child. Published Online First: 19 October 2009. doi:10.1136/adc.2008.152835
Copyright © 2009 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health.
Archives of Disease in Childhood 2009;0:adc.2008.152835
© 2009 BMJ Publishing Group & Royal College of Paediatrics and Child Health

When should we be conducting thyroid function tests in newborns and young infants?

Michael O Ogundele*, Michael Waterson

South Devon Healthcare Trust, Torbay Hospital, Torquay, United Kingdom

Correspondence to: Michael O Ogundele, Community Child Health, South Devon Healthcare Trust, Torbay Hospital, Torquay, 40 Redruth Road, Liverpool, L11 6NA, United Kingdom; m.ogundele{at}nhs.net

Accepted 19 August 2009

ABSTRACT

An audit of local practice was undertaken as regards requests for thyroid function tests (TFT) in children aged between birth and 3 months at two local hospitals in South-West England between 2005 and 2008.

A total of 406 tests were performed (2.6 tests per week) over a two-year period at a teaching hospital (70 tests per 1000 live births yearly), with 233 tests (1.5 tests per week) performed over a three-year period at a local district hospital (39 tests per 1000 live births yearly). The highest proportion of all the tests was performed as routine investigation of prolonged neonatal jaundice (64% and 55% respectively). Other common indications were maternal thyroid disorders (5.4% vs 4.7) and suspected neonatal thyroid disorders (3% vs 9%). There was no confirmed diagnosis of infantile thyroid disease.

Available evidence and this audit suggest that too many thyroid function tests are unnecessarily performed in young infants.


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