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Arch Dis Child. Published Online First: 2 May 2008. doi:10.1136/adc.2008.142356
Copyright © 2008 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health

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Archimedes

Does atomoxetine increase the risk of aggression and hostility in children with attention deficit hyperactivity disorder (ADHD)?

Somnath Banerjee 1* and Hani F Ayyash 2

1 East Kent Hospitals NHS Trust, School & Child Health, Ramsgate, Kent, United Kingdom
2 Doncaster Royal Infirmary, Doncaster, S Yorkshire, United Kingdom

* To whom correspondence should be addressed. E-mail: somnath.b{at}doctors.org.uk.

Accepted 9 April 2008


*   Abstract

Clinical bottom line

1. Aggression and/or hostility can be associated with ADHD (Grade B).

2. Present evidence does not suggest aggression/hostility with atomoxetine compared with methylphenidate or placebo, although it can not be completed ruled out (Grade A).








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