Archives of Disease in Childhood 2008;93:319-320
Short report
Study of antibody titres after measles vaccination: fever within 7 days of vaccination and efficacy of booster doses
1 EGAMI Children’s Clinic, 8–16–63, Kusunoki, Kumamoto 862–8003, Japan
2 Department of Pharmacology, National Research Institute for Child Health and Development, 2–10–1 Okura, Setagaya-ku, Tokyo 157–8535, Japan
Dr Tsuneyoshi Egami, EGAMI Children’s Clinic, 8–16–63, Kusunoki, Kumamoto 862–8003, Japan; egami{at}coral.ocn.ne.jp
We investigated seroconversion rates in febrile children after measles vaccination. Among 6364 vaccinees, 501 children had a temperature of 37.5°C or higher within 7 days of vaccination. The seroconversion rate assessed by a haemagglutination-inhibition assay was 76.6% in 501 febrile children but 95.2% in 84 afebrile controls.
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