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Monitoring of concordance in growth hormone therapy

Department of Paediatrics, Addenbrooke’s Hospital, University of Cambridge, Cambridge, UK

Correspondence to:
Dr C L Acerini, Department of Paediatrics, Addenbrooke’s Hospital, Hills Road, Cambridge CB2 2QQ, UK; cla22{at}cam.ac.uk

Concordance with growth hormone (GH) therapy in 75 children was objectively assessed using data on GP prescriptions over 12 months. 23% missed >2 injections/week. Lower concordance was associated with longer duration on GH therapy (p<0.005), lack of choice of delivery device (p<0.005) and short prescription durations (p<0.005), and predicted lower height velocities (p<0.05).

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				Petrou and McIntosh Measuring the benefits of growth hormone therapy in children: a role for preference-based approaches? Arch. Dis. Child., February 1, 2008; 93(2): 95 - 97. [Full Text] [PDF]