HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS REGISTER		Author Keyword(s) Vol Page [Advanced]

This Article Full Text Full Text (PDF) All Versions of this Article: adc.2007.115980v1 93/1/59    most recent Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Email this link to a friend Similar articles in ADC Online Similar articles in PubMed Add article to my folders Download to citation manager Request Permissions Google Scholar Articles by Struik, S S Articles by Lyall, H PubMed PubMed Citation Articles by Struik, S S Articles by Lyall, H

Infant HIV infection despite "universal" antenatal testing

¹ St Mary’s NHS Trust, London, UK
² Imperial College London, London, UK

Correspondence to:
Dr H Lyall, St Mary’s NHS Trust, Family Clinic, 6th Floor, QEQM Building, Praed Street, London W2 1NY, UK; hermione.lyall{at}St-Marys.nhs.uk

We reviewed the antenatal HIV testing history, clinical presentation and outcome of 25 infants diagnosed with HIV between 1 January 2001 and 31 December 2005 in a tertiary referral hospital in London. Of the 25 cases, 21 had received antenatal care in the UK. Twelve mothers had not had an antenatal HIV test, four had tested positive antenatally, while five had had a negative HIV test on antenatal booking, implying seroconversion in pregnancy. When mothers had not been diagnosed antenatally, infants presented with severe infections, which were fatal in six cases. The majority (65%) of the children have long-term neurological sequelae. HIV seroconversion is an important cause of infant HIV in the UK.