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Live viral vaccines in a DiGeorge syndrome patient

¹ Department of Pediatrics, Division of Infectious Diseases, Hospital for Sick Children, University of Toronto, Toronto, Canada
² Department of Pediatrics, Division of Allergy and Immunology and Division of Autoimmune and Molecular Diseases, Columbia University, New York, NY 10032, USA
³ Department of Pediatrics, Division of Infectious Diseases, Columbia University, New York, NY 10032, USA

Correspondence to:
Correspondence to:
Dr Valerie Waters
Division of Infectious Diseases, The Hospital for Sick Children, 555 University Avenue, Rm 7289, Toronto, Ontario, Canada M5G 1X8; Valerie.waters{at}sickkids.ca

ABSTRACT
We report a case of pneumonia in a 13 month old male child with partial DiGeorge syndrome who died after inadvertently receiving live viral vaccines. Although live viral vaccines have been used safely in some children with DiGeorge syndrome, there are insufficient data to recommend their routine use in those with severe immunodeficiency.

Keywords: DiGeorge syndrome; vaccine; viral

Relevant Article

A brief digest of the June issue
Arch. Dis. Child. 2007 92: e6. [Extract] [Full Text] [PDF]