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Published Online First: 11 August 2006. doi:10.1136/adc.2005.081216
Archives of Disease in Childhood 2007;92:298-303
Copyright © 2007 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health

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ORIGINAL ARTICLE

Blood pressure centiles for Great Britain

Lisa V Jackson1, Nandu K S Thalange2, Tim J Cole3

1 Willow Wood Medical Practice and University of East Anglia School of Medicine, Health Policy and Practice, Norwich, UK
2 Norfolk and Norwich University Hospital, Norwich, UK
3 Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, University College London, London, UK

Correspondence to:
Correspondence to:
Dr L V Jackson
Willow Wood Surgery, Aslake Close, Sprowston, Norwich NR7 8TT, UK; lisa.jackson{at}nhs.net

Objective: To produce representative cross-sectional blood pressure reference centiles for children and young people living in Great Britain.

Design: Analysis of blood pressure data from seven nationally representative surveys: Health Surveys for England 1995–8, Scottish Health Surveys 1995 and 1998, and National Diet & Nutrition Survey 1997.

Methods: Blood pressure was measured using the Dinamap 8100 with the same protocol throughout. Weight and height were also measured. Data for 11 364 males and 11 537 females aged 4–23 years were included in the analysis, after excluding 0.3% missing or outlying data. Centiles were derived for systolic, diastolic, mean arterial and pulse pressure using the latent moderated structural (LMS) equations method.

Results: Blood pressure in the two sexes was similar in childhood, rising progressively with age and more rapidly during puberty. Systolic pressure rose faster and was appreciably higher in adult men than in adult women. After adjustment for age, blood pressure was related more to weight than height, the effect being stronger for systolic blood pressure. Pulse pressure peaked at 18 years in males and 16 years in females.

Conclusions: These centiles increase our knowledge of blood pressure norms in contemporary British children and young people. High blood pressure for age should be defined as blood pressure above the 98th centile, and high-normal blood pressure for age as blood pressure between the 91st and 98th centiles. The centiles identify children and young people with increased blood pressure, and will be of benefit to both clinical practice and research.


Abbreviations: SDS, standard deviation score


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eLetters:

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a definiton of childhood prehypertension is also necessary
oscar,m jolobe
ADC Online, 4 Apr 2007 [Full text]
Blood pressure charts in UK children
Kjell Tullus, et al.
ADC Online, 17 May 2007 [Full text]
Blood pressure centiles for Great Britain – Can they be safely applied to clinical practice?
Anjum Gandhi, et al.
ADC Online, 21 May 2007 [Full text]
Re: Blood pressure charts in UK children
Dr. Narayan Bahadur Basnet
ADC Online, 29 Oct 2007 [Full text]
Re: a definiton of childhood prehypertension is also necessary
Lisa V Jackson, et al.
ADC Online, 25 Mar 2008 [Full text]
Authors' Reply to Blood pressure charts in UK children
Lisa V Jackson, et al.
ADC Online, 1 Apr 2008 [Full text]
Re: Blood pressure centiles for Great Britain – Can they be safely applied to clinical practice?
Lisa V Jackson, et al.
ADC Online, 1 Apr 2008 [Full text]



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