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Archives of Disease in Childhood 2003;88:591-594; doi:10.1136/adc.88.7.591
Copyright © 2003 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health.
Archives of Disease in Childhood 2003;88:591-594
© 2003 BMJ Publishing Group & Royal College of Paediatrics and Child Health

REVIEW

Islet transplant: an option for childhood diabetes?

E Hathout1, J Lakey2, J Shapiro3

1 Director, Pediatric Diabetes Center and Chief, Division of Endocrinology and Diabetes, Loma Linda University Children’s Hospital, Loma Linda, USA
2 Director, Clinical Islet Isolation Laboratory, University of Alberta
3 Director, Clinical Islet Transplant Program and Clinical Research Chair in Transplantation, University of Alberta

Correspondence to:
Correspondence to:
Dr J Shapiro, Director, Clinical Islet Transplant Program, Clinical Research Chair in Transplantation (CIHR/Wyeth Canada), Roberts Centre, University of Alberta, 2000 College Plaza, 8215 112 St, Edmonton AB, Canada T6G 2C8;
amjs{at}islet.ca

ABSTRACT

Careful assessment of the safety and efficacy of islet transplantation should guide the selection process of a small number of children with type 1 diabetes who may be eligible for the procedure—some of whom are already receiving immunosuppression because of a previous transplant, others who are scheduled to receive de novo islet alone transplantation because of a life threatening risk of hypoglycemia. The outcomes of these initial investigations are predicted to shape the future boundaries of islet transplantation, diabetes, and transplantation.

Keywords: islet transplant; diabetes


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Arch. Dis. Child. 2003 88: 557. [Extract] [Full Text] [PDF]

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