© 2003 BMJ Publishing Group & Royal College of Paediatrics and Child Health
REVIEW
Acute disseminated encephalomyelitis: recognition in the hands of general paediatricians
1 Department of Paediatric Neurology, Birmingham Children’s Hospital, Birmingham, UK
2 Department of General Paediatrics, Walsgrave Hospital, Coventry, UK
3 Academic Division of Child Health, University of Nottingham, Nottingham, UK
Correspondence to:
Correspondence to:
Dr W P Whitehouse, Senior Lecturer in Paediatric Neurology, Academic Division of Child Health, E Floor East Block, Queen’s Medical Centre, Nottingham NG7 2UH, UK;
william.whitehouse{at}nottingham.ac.uk
Acute disseminated encephalomyelitis will often present to the general paediatrician as an acute polysymptomatic encephalopathy, and initially the diagnosis may not be clear. A brain MRI scan is essential in establishing the diagnosis and so enabling appropriate advice and treatment to be given. Multicentre clinical audit of outcome and controlled therapeutic trials are needed to secure an evidence base for current practice.
Keywords: ADEM; demyelination; multiple sclerosis; MRI; diagnosis
Abbreviations: ADEM, acute disseminated encephalomyelitis; CSF, cerebrospinal fluid; CT, computed tomography; MRI, magnetic resonance imaging; MS, multiple sclerosis
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