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Archives of Disease in Childhood 2002;87:337-338; doi:10.1136/adc.87.4.337
Copyright © 2002 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health.
Archives of Disease in Childhood 2002;87:337-338
© 2002 Archives of Disease in Childhood

CASE REPORT

Hypopituitarism following cerebral oedema with diabetic ketoacidosis

K A Dunlop1, D Woodman1, D J Carson2

1 Royal Belfast Hospital for Sick Children, Northern Ireland, UK
2 Department of Child Health, Queens University, Belfast, Northern Ireland, UK

Correspondence to:
Correspondence to:
Dr D J Carson, Department of Child Health, Institute of Clinical Science, Grosvenor Road, Belfast BT12 6BJ, Northern Ireland, UK;
d.carson{at}qub.ac.uk

ABSTRACT

Clinical evidence of cerebral oedema occurs in approximately 1% of diabetic ketoacidosis episodes. Mortality from this serious complication is falling, but little is known of long term outcome. We describe hypopituitarism and executive dysfunction developing two years after cerebral oedema complicating diabetic ketoacidosis in a 12 year old with type 1 diabetes.

Keywords: hypopituitarism; cerebral oedema; diabetic ketoacidosis

Abbreviations: CT, computed tomography; DKA, diabetic ketoacidosis; FT4, free thyroxine; Htvel, height velocity; IGF, insulin-like growth factor; TSH, thyroid stimulating hormone


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This article has been cited by other articles:

  • Dunger, D B, Sperling, M A, Acerini, C L, Bohn, D J, Daneman, D, Danne, T P A, Glaser, N S, Hanas, R, Hintz, R L, Levitsky, L L, Savage, M O, Tasker, R C, Wolfsdorf, J I (2004). ESPE/LWPES consensus statement on diabetic ketoacidosis in children and adolescents. Arch. Dis. Child. 89: 188-194 [Abstract] [Full Text]  
  • Dunger, D. B., Sperling, M. A., Acerini, C. L., Bohn, D. J., Daneman, D., Danne, T. P.A., Glaser, N. S., Hanas, R., Hintz, R. L., Levitsky, L. L., Savage, M. O., Tasker, R. C., Wolfsdorf, J. I. (2004). European Society for Paediatric Endocrinology/Lawson Wilkins Pediatric Endocrine Society Consensus Statement on Diabetic Ketoacidosis in Children and Adolescents. Pediatrics 113: e133-140 [Full Text]  

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