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Archives of Disease in Childhood 2002;87:252-254; doi:10.1136/adc.87.3.252
Copyright © 2002 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health.
Archives of Disease in Childhood 2002;87:252-254
© 2002 Archives of Disease in Childhood

SHORT REPORT

Phase angle and n-3 polyunsaturated fatty acids in sickle cell disease

D J VanderJagt1, Y-S Huang2, L-T Chuang2, C Bonnett1, R H Glew1

1 Department of Biochemistry and Molecular Biology, University of New Mexico, School of Medicine, Albuquerque, NM 87131, USA
2 Ross Products Division, Abbott Laboratories, Columbus, Ohio, USA

Correspondence to:
Correspondence to:
Dr R H Glew, Department of Biochemistry and Molecular Biology, Room 249, BMSB, University of New Mexico, School of Medicine, Albuquerque, NM 87131, USA;
rglew{at}salud.unm.edu

ABSTRACT

Phase angle, an impedance parameter used for nutritional assessment, is reflective of the capacitance properties of cell membranes. We have shown a significant correlation between the proportions of specific n-3 polyunsaturated fatty acids in the serum phospholipids of Nigerian children with sickle cell disease and their phase angles determined by bioelectrical impedance analysis.

Keywords: polyunsaturated fatty acid; sickle cell disease; phase angle

Abbreviations: BIA, bioelectrical impedance analysis; SCD, sickle cell disease


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