© 2002 Archives of Disease in Childhood
SHORT REPORT
Erythromelalgia: an endothelial disorder responsive to sodium nitroprusside
1 Departments of Nephrology, Dermatology, and Psychological Medicine, Great Ormond Street Hospital for Children, London WC1N 3JH, UK
2 Clinical Microvascular Unit, St Bartholomews Hospital, London, UK
Correspondence to:
Correpondence to:
Professor M J Dillon, Renal Unit, Great Ormond Street Hospital for Children, London WC1N 3JH, UK;
M.Dillon{at}ich.ucl.ac.uk
Erythromelalgia is an unusual syndrome of painful vasodilatation. Aetiopathology is probably different in children and adults. Presentation can be severe and associated with hypertension. Dramatic benefit from infused nitroprusside suggests the disorder could represent a dysfunctional endothelium.
Keywords: erythromelalgia; sodium nitroprusside; vasodilatation
Abbreviations: EM, erythromelalgia; SNP, sodium nitroprusside
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