© 2002 Archives of Disease in Childhood
SHORT REPORT
Clinical validation for oxacillin susceptibility testing of coagulase negative staphylococci
1 Program of Microbiology, Virology, and Infection Control, Department of Pathology and Laboratory Medicine, Children's and Women's Health Centre of British Columbia, Canada
2 Division of Paediatric Nephrology, Department of Paediatrics, Children's and Women's Health Centre of British Columbia, Canada
Oxacillin susceptibility of coagulase negative staphylococci as assessed by conventional methods was confirmed by a modified Etest method, extended to detect heteroresistance. Verification of susceptibility was followed by successful treatment for six consecutive children with deep seated infections. Physicians' trust in such a validated method will contribute to the appropriate use of antibiotics.
Keywords: staphylococcus; oxacillin; susceptibility testing
Abbreviations: CNS, coagulase negative staphylococci; MIC, minimal inhibitory concentration; MRSA, methicillin resistant S aureus
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