Article
Fine needle aspiration biopsy of thyroid nodules
I S Ardaa, S Yildirima, B Demirhana, S Firatb
a Baskent
University Faculty of Medicine, Department of Pediatric Surgery, Fevzi
Çakmak caddesi 10. sokak No: 45, 06490 Bahçelievler Ankara, Turkey, b Social Security Hospital Ankara Children
Hospital, Division of Pediatrics
Correspondence to: Prof. Serdar serdara{at}baskent-ank.edu.tr
Accepted 25 June 2001
BACKGROUND
Fine needle aspiration
biopsy (FNA) is a routine diagnostic technique for evaluating thyroid
nodules. Many reports in adults consider that FNA is superior to
thyroid ultrasonography (USG) and radionuclide scanning (RS). Only five
studies have been published on FNA of childhood thyroid nodules.
AIMSTo investigate the reliability
of FNA in the evaluation and management of thyroid nodules, and compare
the results of FNA, USG, and RS with regard to final histopathological diagnosis.
METHODSFNA was performed in 46 children with thyroid nodules after USG and RS examination. We
investigated the sensitivity, specificity, accuracy, and positive and
negative predictive values of USG, RS, and FNA in their management.
RESULTSSix patients who had
malignant or suspicious cells on FNA examination underwent immediate
surgery. The other 40 patients received medical treatment according to
their hormonal status. Fifteen of these nodules either disappeared or
decreased in number and/or size. Surgery was performed in 25 patients
who did not respond to therapy. Statistical analysis revealed
sensitivity, specificity, accuracy, and positive and negative
predictive values respectively as follows: 60%, 59%, 59%, 15%, and
92% for USG; 30%, 42%, 39%, 12%, and 68% for SC; 100%, 95%,
95%, 67%, and 100% for FNAB.
CONCLUSIONFNAB is as reliable in
children as in adults for definitive diagnosis of thyroid nodules.
Using this technique avoids unnecessary thyroid surgery in children.
Keywords: fine needle aspiration; biopsy; thyroid nodule
© 2001 by Archives of Disease in Childhood
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