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Crushed prednisolone tablets or oral solution for acute asthma?
M E Lucas-Bouwmana, R J Roordaa, F G A Jansmanb, P L P Branda
a Department of
Paediatrics, Isala klinieken/Weezenlanden Hospital, PO Box 10500, 8000 GM Zwolle, Netherlands, b Department of Clinical
Pharmacy, Isala klinieken/Weezenlanden Hospital
Correspondence to: Dr Brand P.L.P.Brand{at}isala.nl
Accepted 27 November
2000
In a randomised trial, treatment with prednisolone in two
formulations (oral solution or crushed tablets) was compared in 78 young children with acute asthma. Prednisolone oral solution was better
tolerated than crushed tablets (less vomiting, superior taste);
clinical resolution was similar.
Keywords: acute asthma; prednisolone; oral solution; powder; formulation
© 2001 by Archives of Disease in Childhood
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