Article
Re-vaccination of 421 children with a past history of an adverse
vaccine reaction in a special immunisation service
Michael Gold, Helen Goodwin, Sue Botham, Margaret Burgess, Margot Nash, Ann Kempe
South Australian
Immunisation Coordination Unit, Communicable Disease Control Branch,
Department of Human Services, PO Box 6, Rundle Mall, Adelaide 5000, South Australia
Correspondence to: Dr Gold email: mgold{at}medicine.adelaide.edu.au
Accepted 24 March 2000
BACKGROUND
In Australia an adverse
event following immunisation (AEFI), with the exception of anaphylaxis
and encephalopathy, is no longer considered an absolute
contraindication to continuing vaccination with the suspect vaccine.
Despite these recommendations there is a paucity of information on the
re-vaccination of such children.
AIMSTo describe the re-vaccination
of a large number of children with a past history of an AEFI.
METHODSA review of children
attending special immunisation services in three Australian tertiary
care paediatric centres.
RESULTSDuring the review 970 children attended of whom 469 had experienced a past AEFI. Of these,
293 had experienced minor while 176 children had experienced
significant neurological or allergic reactions. The majority (421/469)
were re-vaccinated, with only one child having a significant
neurological event; this was transient and resolved spontaneously.
CONCLUSIONSRe-vaccination of
children who have a past history of an AEFI appears safe. A special
immunisation service should be part of a comprehensive immunisation programme.
Keywords: immunisation; adverse event following immunisation; adverse vaccine reactions
© 2000 by Archives of Disease in Childhood
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