Article
Height and weight reference curves for homozygous sickle cell
disease
P W Thomasa, A Singhalb, M Hemmings-Kellyc, G R Serjeantc
a Research and
Development Support Unit, Institute of Health and Community Studies,
Bournemouth University, Royal London House, Christchurch Road,
Bournemouth BH1 3LT, UK, b MRC
Childhood Nutrition Research Centre, Institute of Child Health, London
WC1N 1EH, UK, c MRC Laboratories,
University of the West Indies, Kingston 7, Jamaica
Correspondence to: Dr Thomas email: pthomas{at}bournemouth.ac.uk
Accepted 13 August
1999
OBJECTIVE
To derive
height and weight growth reference curves for children with homozygous
sickle cell disease.
STUDY DESIGNSubjects
(n = 315) were participants in a population based, longitudinal
cohort study of sickle cell disease in Kingston, Jamaica. Regular
measurements of height and weight were made from enrollment into the
study at birth up to 22 years of age.
RESULTSSex specific
growth reference curves for height for age and weight for age covering
the age range 0-18 years are presented.
CONCLUSIONThese
growth reference curves are suitable for identifying coincidental
growth problems in children with homozygous sickle cell disease.
Keywords: growth; reference; sickle cell disease
© 2000 by Archives of Disease in Childhood
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