Arch Dis Child 1999;80:69-71 ( January )

Long term neurological outcome of herpes encephalitis

E Lahat,^a J Barr,^a G Barkai,^a G Paret,^b N Brand,^a A Barzilai^b

^a Paediatric Department, Assaf Harofeh Medical Center, Zerifin, Israel, ^b Paediatric Infections Unit, Sheba Medical Centre, Tel Hashomer, Israel

Correspondence to: Dr E Lahat, Paediatric Neurology Clinic, Assaf Harofeh Medical Center, Zerifin 70300, Israel.

Accepted 4 August 1998

Twenty eight children with herpes simplex encephalitis were followed up for a mean of 5.5 years. Two children died and 26 survived, of whom 16 were left with no neurological sequelae and 10 had persistent neurological sequelae. Mean (SD) Glasgow coma score was significantly lower in the patients with neurological sequelae (7.7 (1.5)) and the patients who died (4.5 (0.7)), compared with the patients without neurological sequelae (11 (1.7)).

Keywords: herpes simplex; encephalitis

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© 1999 by Archives of Disease in Childhood
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