Melatonin treatment in an institutionalised child with psychomotor retardation and an irregular sleep-wake pattern
a Pediatrics
Department A, Rambam Medical Center, Haifa 31096, Israel, b Sleep
Laboratory, Gutwirth Building, Technion-IIT, Haifa, Israel
Correspondence to: Dr Pillar, MD.
Accepted 5 January
1998
An institutionalised 13 year old girl with psychomotor
retardation suffered from an irregular sleep-wake pattern. Multiple measurements of urinary sulphatoxymelatonin (aMT6) concentrations were abnormally low, without any significant day-night differences. Administration of exogenous melatonin (3 mg) at 18:00 resulted in
increased nocturnal urinary aMT6 concentrations and improvements in her
sleep-wake pattern. Melatonin may help disabled children suffering
from sleep disorders.
© 1998 by Archives of Disease in Childhood
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
This article has been cited by other articles:
-
Turk, J
(2003). Melatonin supplementation for severe and intractable sleep disturbance in young people with genetically determined developmental disabilities: short review and commentary. J. Med. Genet.
40: 793-796
[Abstract] [Full Text]
- Full Text
- Full Text (PDF)
- Submit a response
- Alert me when this article is cited
- Alert me when eLetters are posted
- Alert me if a correction is posted
- Citation Map
Services
- Email this link to a friend
- Similar articles in ADC Online
- Similar articles in PubMed
- Add article to my folders
- Download to citation manager
- Request Permissions
Citing Articles
Google Scholar
PubMed
Topic Collections
-
Child health
-
Sleep disorders (neurology)
-
Sleep disorders
-
Disability
- Sleep disorders (respiratory medicine)
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
