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Archives of Disease in Childhood 1998;78:367-370; doi:10.1136/adc.78.4.367
Copyright © 1998 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health.
Arch Dis Child 1998;78:367-370 ( April )

Arthritis as a presenting feature of non-Hodgkin's lymphoma

Fernanda Falcini,a Maria Bardare,b Rolando Cimaz,b Alma Lippi,a Fabrizia Coronab

a Department of Paediatrics, University of Florence, Italy, b Department of Paediatrics, University of Milan, Italy

Correspondence to: and reprint requests to: Dr Rolando Cimaz, Clinica Pediatrica, Via Commenda 9, 20122 Milano, Italy.


Accepted 30 September 1997

Leukaemia can present with joint swelling in the absence of abnormal haematological findings. Arthritis as a presenting sign of lymphoma, however, is extremely rare. Three children with non-Hodgkin's lymphoma who had joint swelling at the onset of their disease are reported. Two cases showed histological features of anaplastic large cell lymphoma (Ki-l/CD30 positive), and one of angioimmunoblastic T cell lymphoma. In all patients the unusual presentation delayed correct diagnosis.

Keywords: lymphoma; arthritis; juvenile chronic arthritis


© 1998 by Archives of Disease in Childhood

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