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Archives of Disease in Childhood 1997;77:210-213; doi:10.1136/adc.77.3.210
Copyright © 1997 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health.
Arch Dis Child 1997;77:210-213 ( September )

Rising incidence of type 1 diabetes in Scottish children, 1984-93

Jayanti J Rangasami,a Darren C Greenwood,b Brenda McSporran,c Peter J Smail,c Chris C Patterson,d Norman R Waughe, on behalf of the Scottish Study Group for the Care of Young Diabetics

a West Middlesex University Hospital, Isleworth, b Nuffield Institute for Health, Leeds University, c Royal Aberdeen Children's Hospital, d Department of Epidemiology and Public Health, Queen's University of Belfast, e Public Health Medicine, Aberdeen

Correspondence to: Dr Jayanti J Rangasami, West Middlesex University Hospital, Twickenham Road, Isleworth, Middlesex TW7 OAF.


Accepted 30 May 1997

OBJECTIVES---To calculate the incidence of type 1 diabetes in Scottish children aged less than 15 years between 1984 and 1993; to examine changes in incidence; and to calculate the prevalence of diabetes at the end of this period.
DESIGN---Three data sources were used to construct the Scottish Study Group for the Care of Young Diabetics register: active reporting of all new cases; reports from the Scottish Morbidity Register 1; and local registers.
SUBJECTS---All children resident in Scotland diagnosed with primary insulin dependent diabetes mellitus when less than 15 years of age between 1984 and 1993.
MAIN OUTCOME MEASURES---Annual incidence and prevalence rate for Scotland; time trend in incidence over the 10 years; differences in incidence between the three different age groups; and completeness of the register.
RESULTS---The average annual incidence for Scotland was 23.9/100 000 children. The prevalence rate was 1.5/1000 in 1993. A total of 2326 cases was identified from the three sources. Capture-recapture analysis suggests a case ascertainment of 98.6%. The annual incidence rates increased at a rate of 2% each year (rate ratio = 1.02, 95% confidence interval (CI) 1.01 to 1.03). The incidence was higher in boys than girls (rate ratio = 1.08, 95% CI 1.00 to 1.18), and the incidence rates increased with age: 15.3/100 000/year for age 0-4 years, 24.4/100 000/year for age 5-9 years, and 31.9/100 000/year for age 10-14 years.
CONCLUSIONS---The incidence of type 1 diabetes in Scotland is increasing and the prevalence is relatively high. These findings have important implications for health service resource allocation. The Scottish Study Group for the Care of Young Diabetics' register provides a base for monitoring and research.

Keywords: insulin dependent diabetes mellitus; environmental triggers; genetic susceptibility; prevalence


© 1997 by Archives of Disease in Childhood

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