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Archives of Disease in Childhood 1997;76:532-534; doi:10.1136/adc.76.6.532
Copyright © 1997 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health.
Arch Dis Child 1997;76:532-534 ( June )

Severe malabsorption in autoimmune polyendocrinopathy-candidosis-ectodermal dystrophy syndrome successfully treated with immunosuppression

S Padeh, R Theodor, A Jonas, J H Passwell

Department of Paediatrics, Chaim Sheba Medical Centre, Affiliated to the Tel-Aviv University, Sackler School of Medicine, Tel Hashomer, Israel

Correspondence to: Dr S Padeh, Paediatric Department B, Chaim Sheba Medical Centre, Affiliated to the Tel-Aviv University, Sackler School of Medicine, Tel Hashomer 52621, Israel.

Accepted 2 January 1997

A 15 year old boy with autoimmune polyendocrinopathy-candidosis-ectodermal dystrophy syndrome suffered recurrent episodes of severe intractable diarrhoea, steatorrhoea, and hypocalcaemia. The only treatment modality, which controlled the malabsorption syndrome, was immunosuppression with intravenous high dose methylprednisolone and oral methotrexate maintenance therapy.

Keywords: autoimmune polyendocrinopathy-candidosis-ectodermal-dystrophy syndrome; malabsorption; immunosuppression


© 1997 by Archives of Disease in Childhood

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