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Archives of Disease in Childhood 1990;65:703-704; doi:10.1136/adc.65.7_Spec_No.703
Copyright © 1990 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health.

Topical prostaglandin E2 gel for cervical ripening and closure of the ductus arteriosus in the newborn.

R Y Sung, J A Yin, E P Loong, T F Fok, J Lau

Department of Paediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin.

The closure time of the ductus arteriosus was investigated in 29 full term babies born vaginally after induction with prostaglandin E2 and in 22 controls. Serial Doppler echocardiography studies showed a significantly prolonged closure time in babies induced by prostaglandin E2. Whether the difference is related to changes in fetal prostaglandin E2 concentration remains to be established.


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