Weight gain and height velocity during prolonged first remission from acute lymphoblastic leukaemia.

C P Sainsbury, R G Newcombe, I A Hughes

A retrospective analysis of the medical records of 86 children in prolonged remission from acute lymphoblastic leukaemia was performed to calculate changes in the rate of increase in height and weight gain. The rate of increase in height decreased during initial treatment, and the potential for final adult height was not regained. Weight gain was excessive; this started during treatment and persisted into the remission years. Values of weight adjusted for height did not return to values found before treatment until eight years after diagnosis. Several factors can account for this weight gain, but there is a practical need to provide dietary advice, particularly when chemotherapy is stopped.

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

• Jarfelt, M, Lannering, B, Bosaeus, I, Johannsson, G, Bjarnason, R (2005). Body composition in young adult survivors of childhood acute lymphoblastic leukaemia. Eur J Endocrinol 153: 81-89 [Abstract] [Full Text]  
• Warner, J T, Evans, W D, Webb, D K H, Gregory, J W (2004). Pitfalls in the assessment of body composition in survivors of acute lymphoblastic leukaemia. Arch. Dis. Child. 89: 64-68 [Abstract] [Full Text]  
• Lustig, R. H., Post, S. R., Srivannaboon, K., Rose, S. R., Danish, R. K., Burghen, G. A., Xiong, X., Wu, S., Merchant, T. E. (2003). Risk Factors for the Development of Obesity in Children Surviving Brain Tumors. J. Clin. Endocrinol. Metab. 88: 611-616 [Abstract] [Full Text]  
• (1999). Degree of Fatness after Treatment for Acute Lymphoblastic Leukemia in Childhood. J. Clin. Endocrinol. Metab. 84: 4591-4596 [Abstract] [Full Text]  
• Birkebæk, N H, Clausen, N (1998). Height and weight pattern up to 20 years after treatment for acute lymphoblastic leukaemia. Arch. Dis. Child. 79: 161-164 [Abstract] [Full Text]  
• Cicognani, A., Cacciari, E., Carla, G., Rosito, P., Cau, M., Mancini, A. F., Zucchini, S., Vecchi, V., Pirazzoli, P., Paolucci, G. (1992). Magnetic Resonance Imaging of the Pituitary Area in Children Treated for Acute Lymphoblastic Leukemia With Low-Dose (18-Gy) Cranial Irradiation: Relationships to Growth and Growth Hormone Secretion. Arch Pediatr Adolesc Med 146: 1343-1348 [Abstract]  
• Cicognani, A., Cacciari, E., Vecchi, V., Cau, M., Balsamo, A., Pirazzoli, P., Tosi, M. T., Rosito, P., Paolucci, G. (1988). Differential Effects of 18- and 24-Gy Cranial Irradiation on Growth Rate and Growth Hormone Release in Children With Prolonged Survival After Acute Lymphocytic Leukemia. Arch Pediatr Adolesc Med 142: 1199-1202 [Abstract]