Urine albumin to creatinine ratio-response to exercise in diabetes.

I G Jefferson, S A Greene, M A Smith, R F Smith, N K Griffin, J D Baum

Albuminuria was studied in 40 diabetic children before and after a standardised exercise test, and also in 21 normal children; the results are expressed as geometric mean (95% range) of urine albumin:urine creatinine ratio (mg/mg). There was no significant difference between the mean resting albumin:creatinine ratio in the two groups, or between these ratios before and after exercise in the normal children. In the diabetic children, however, the mean urine albumin:creatinine ratio after exercise was significantly higher than both the value before exercise and the postexercise value of the normal children, with 10 of 40 diabetic children showing a value after exercise greater than the 95% range of the geometric mean of the control group. The diabetic children were also studied by random urine albumin:creatinine ratios and split (erect:supine) 24 hour urine collection; none was abnormal.

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

Relevant Article

Commentary

V Matti Vehaskari
Arch. Dis. Child. 1985 60: 309-310. [PDF]

This article has been cited by other articles:

• Hogg, R. J., Furth, S., Lemley, K. V., Portman, R., Schwartz, G. J., Coresh, J., Balk, E., Lau, J., Levin, A., Kausz, A. T., Eknoyan, G., Levey, A. S. (2003). National Kidney Foundation's Kidney Disease Outcomes Quality Initiative Clinical Practice Guidelines for Chronic Kidney Disease in Children and Adolescents: Evaluation, Classification, and Stratification. Pediatrics 111: 1416-1421 [Abstract] [Full Text]  
• Heintz, B., Stocker, G., Mrowka, C., Rentz, U., Melzer, H., Stickeler, E., Sieberth, H.-G., Greiling, H., Haubeck, H.-D. (1995). Decreased Glomerular Basement Membrane Heparan Sulfate Proteoglycan in Essential Hypertension. Hypertension 25: 399-407 [Abstract] [Full Text]