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Archives of Disease in Childhood 1980;55:810-812; doi:10.1136/adc.55.10.810
Copyright © 1980 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health.

D-Lactic acidosis in a boy with short bowel syndrome.

E P Schoorel, M A Giesberts, W Blom, H H van Gelderen

Metabolic acidosis in a 3-year-old child with short bowel syndrome led to the discovery of massive D-lactic aciduria. After normalisation of the intestinal bacterial flora, D-lactate disappeared together with the acidosis. Dysbacteriosis with excessive production of D-lactate by intestinal bacteria (unidentified) and subsequent absorption explains this unusual cause of metabolic acidosis.


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This article has been cited by other articles:

  • Karton, M. A., Rettmer, R., Lipkin, E. W., Ott, S. M., Chait, A. (1989). D-Lactate and Metabolic Bone Disease in Patients Receiving Long-Term Parenteral Nutrition. JPEN J Parenter Enteral Nutr 13: 132-135 [Abstract]  
  • Karton, M., Rettmer, R. L., Lipkin, E. W. (1987). Effect of Parenteral Nutrition and Enteral Feeding on D-Lactic Acidosis in a Patient with Short Bowel. JPEN J Parenter Enteral Nutr 11: 586-589 [Abstract]  
  • Ramakrishnan, T., Stokes, P. (1985). Beneficial Effects of Fasting and Low Carbohydrate Diet in D-Lactic Acidosis Associated with Short-Bowel Syndrome. JPEN J Parenter Enteral Nutr 9: 361-363 [Abstract]  
  • TRAUBE, M., BOCK, J. L., BOYER, J. L. (1983). D-Lactic Acidosis After Jejunoileal Bypass: Identification of Organic Anions by Nuclear Magnetic Resonance Spectroscopy. ANN INTERN MED 98: 171-173 [Abstract]  

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