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Archives of Disease in Childhood 1980;55:771-775; doi:10.1136/adc.55.10.771
Copyright © 1980 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health.

Misleading plasma electrolytes in diabetic children with severe hyperlipidaemia.

B M Frier, C R Steer, J D Baird, S Bloomfield

Severe abnormalities of plasma electrolyte concentrations were observed in 4 children who had massive hyperlipidaemia secondary to poorly-controlled, insulin-dependent diabetes mellitus. These electrolyte values were fallacious and invoked problems of clinical management, particularly with regard to fluid replacement. Each case is described and the interpretation of plasma elecytolyte values in hyperlipidaemia is discussed.


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  • Bhowmick, S. K., Hundley, O. T., Rettig, K. R. (2007). Severe Hypernatremia and Hyperosmolality Exacerbated by an Herbal Preparation in a Patient With Diabetic Ketoacidosis. CLIN PEDIATR 46: 831-834 [Abstract]  
  • Turchin, A., Seifter, J. L., Seely, E. W. (2003). Mind the Gap. NEJM 349: 1465-1469 [Full Text]  
  • Howard, J. M., Reed, J. (1985). Pseudohyponatremia in Acute Hyperlipemic Pancreatitis: A Potential Pitfall in Therapy. Arch Surg 120: 1053-1055 [Abstract]  
  • SHEHADEH, N., BENDERLY, A., ERDE, P., ETZIONI, A. (1984). Factitious Hyponatremia in a Child. Arch Pediatr Adolesc Med 138: 1085-1085 [Abstract]  
  • LADENSON, J. H., APPLE, F. S., KOCH, D. D. (1981). Misleading Hyponatremia Due to Hyperlipemia: A Method-Dependent Error. ANN INTERN MED 95: 707-708 [Abstract]  

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